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| French Open | ||
| Surface: Red Clay | Date: May 28 - Jun. 10 | Seed: 21 |
| Round | Opponent | W / L | Result |
| First Round | Leylah Fernandez | Loss | 3-6, 6-1, 3-6 |
| Internationaux de Strasbourg | ||
| Surface: Clay | Date: May 21 - May 27 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Cristina Bucsa | Win | 4-6, 6-2, 6-2 |
| Second Round | Anastasia Pavlyuchenkova | Loss | 3-6, 2-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 9 - May 21 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Linda Noskova | Win | 7-6 (7-4), 6-1 |
| Third Round | Beatriz Haddad Maia | Loss | 5-7, 4-6 |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 25 - May 6 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marketa Vondrousova | Win | 7-6 (7-1), 4-6, 6-4 |
| Third Round | Mirra Andreeva | Loss | 3-6, 3-6 |
| Credit One Charleston Open | ||
| Surface: Green Clay | Date: Apr. 3 - Apr. 9 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Varvara Gracheva | Win | 6-7 (3-7), 7-5, 6-4 |
| Third Round | Madison Keys | Loss | 2-6, 6-3, 1-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 21 - Apr. 1 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Evgeniya Rodina | Win | 6-3, 6-4 |
| Third Round | Victoria Azarenka | Win | 7-6 (7-3), 2-6, 6-4 |
| Fourth Round | Jessica Pegula | Loss | 1-6, 5-7 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 8 - Mar. 19 | Seed: 20 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Emma Raducanu | Loss | 6-7 (3-7), 2-6 |
| ATX Open | ||
| Surface: Hard | Date: Feb. 27 - Mar. 5 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Varvara Gracheva | Loss | 3-6, 6-4, 4-6 |
| Mérida Open Akron | ||
| Surface: Hard | Date: Feb. 20 - Feb. 27 | Seed: 1 |
| Round | Opponent | W / L | Result |
| Second Round | Panna Udvardy | Win | 6-0, 2-5 Retired |
| Quarterfinals | Rebecca Peterson | Loss | 2-6, 4-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mayar Sherif | Win | |
| Second Round | Anett Kontaveit | Win | |
| Third Round | Ekaterina Alexandrova | Win | |
| Fourth Round | Caroline Garcia | Win | |
| Quarterfinals | Karolina Pliskova | Win | |
| Semifinals | Aryna Sabalenka | Loss |
| Hobart International | ||
| Surface: Hard | Date: Jan. 8 - Jan. 14 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Alison Van Uytvanck | Loss |
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