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| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 11 - Aug. 18 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Jordan Thompson | Win | 7-5, 5-7, 6-4 |
| Second Round | Kei Nishikori | Win | 7-6 (7-2), 6-4 |
| Third Round | Alex De Minaur | Win | 7-5, 6-4 |
| Quarterfinals | David Goffin | Loss | Retired |
| Citi Open | ||
| Surface: Hard | Date: Jul. 29 - Aug. 4 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Daniel Evans | Win | 6-4, 6-1 |
| Second Round | David Goffin | Win | 6-7 (5-7), 6-2, 7-6 (7-5) |
| Third Round | Nick Kyrgios | Loss | 2-6, 5-7 |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Janko Tipsarevic | Loss | 4-6, 7-6 (7-2), 2-6, 7-5, 2-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mackenzie McDonald | Win | 6-7 (7-9), 6-0, 4-6, 6-2, 6-3 |
| Second Round | Juan Martin Del Potro | Loss | 7-5, 4-6, 2-6, 7-6 (7-5), 2-6 |
| Banque Eric Sturdza Geneva Open | ||
| Surface: Clay | Date: May 19 - May 25 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ernests Gulbis | Loss | 2-6, 6-7 (7-9) |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 12 - May 19 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss | 1-6, 4-6 |
| Millennium Estoril Open | ||
| Surface: Red Clay | Date: Apr. 29 - May 5 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mackenzie McDonald | Win | 6-2, 6-4 |
| Second Round | Frances Tiafoe | Loss | 6-2, 3-6, 6-7 (5-7) |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 22 - Apr. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Diego Schwartzman | Loss | 6-4, 4-6, 2-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Denis Kudla | Win | 3-6, 6-3, 6-2 |
| Second Round | Roberto Bautista Agut | Win | 7-6 (7-3), 6-4 |
| Third Round | Felix Auger-Aliassime | Win | 6-7 (2-7), 6-4, 7-6 (7-5) |
| Fourth Round | Miomir Kecmanovic | Loss | 4-6, 0-0 Retired |
| Abierto Mexicano TELCEL presentado por HSBC | ||
| Surface: Hard | Date: Feb. 25 - Mar. 3 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cameron Norrie | Loss | 2-6, 6-2, 2-6 |
| Delray Beach Open by VITACOST.com | ||
| Surface: Hard | Date: Feb. 18 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Juan Martin Del Potro | Loss | 3-6, 5-7 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Tennys Sandgren | Win | 6-4, 7-6 (7-5), 4-6, 6-4 |
| Second Round | Karen Khachanov | Loss | 3-6, 3-6, 3-6 |
| Sydney International | ||
| Surface: Hard | Date: Jan. 6 - Jan. 12 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Ryan Harrison | Win | 6-4, 6-2 |
| Second Round | Andrey Rublev | Win | 6-3, 6-1 |
| Quarterfinals | Diego Schwartzman | Loss | 1-6, 6-3, 6-7 (1-7) |
| Brisbane International presented by Suncorp | ||
| Surface: Hard | Date: Dec. 31 - Jan. 6 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Grigor Dimitrov | Loss | 3-6, 4-6 |
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