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| Sofia Open | ||
| Surface: Hard | Date: Sep. 26 - Oct. 2 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye |
| US Open | ||
| Surface: Hard | Date: Aug. 29 - Sep. 11 | Seed: 12 |
| Round | Opponent | W / L | Result |
| First Round | Dominic Thiem | Win | 7-5, 6-1, 5-7, 6-3 |
| Second Round | Alexander Bublik | Win | 4-6, 6-4, 6-3, 7-6(7-5) |
| Third Round | Alex de Minaur | Win | 6-1, 6-1, 3-6, 7-6(7-5) |
| Fourth Round | Karen Khachanov | Loss | 6-4, 3-6, 1-6, 6-4, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 14 - Aug. 21 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Miomir Kecmanovic | Loss |
| Open de la Banque Nationale presentee par Rogers | ||
| Surface: Hard | Date: Aug. 8 - Aug. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Matteo Berrettini | Win | |
| Second Round | Holger Rune | Win | |
| Third Round | Jannik Sinner | Win | |
| Quarterfinals | Jack Draper | Win | |
| Semifinals | Daniel Evans | Win | |
| Final | Hubert Hurkacz | Win |
| Hamburg European Open | ||
| Surface: Red Clay | Date: Jul. 17 - Jul. 24 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Luca Nardi | Win | |
| Second Round | Alex Molcan | Loss |
| Nordea Open | ||
| Surface: Clay | Date: Jul. 11 - Jul. 17 | Seed: 5 |
| Round | Opponent | W / L | Result |
| First Round | Stan Wawrinka | Win | |
| Second Round | Albert Ramos-Vinolas | Win | |
| Quarterfinals | Diego Schwartzman | Win | |
| Semifinals | Francisco Cerundolo | Loss |
| Wimbledon | ||
| Surface: Grass | Date: Jun. 27 - Jul. 10 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Dusan Lajovic | Loss |
| Mallorca Championships | ||
| Surface: Grass | Date: Jun. 19 - Jun. 25 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Antoine Bellier | Loss |
| Terra Wortmann Open | ||
| Surface: Grass | Date: Jun. 13 - Jun. 19 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Holger Rune | Win | |
| Second Round | Sebastian Korda | Win | |
| Quarterfinals | Nick Kyrgios | Loss |
| Roland Garros | ||
| Surface: Red Clay | Date: May 22 - Jun. 5 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Gilles Simon | Loss |
| Open Parc Auvergne-Rhone-Alpes Lyon | ||
| Surface: Clay | Date: May 15 - May 21 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Federico Coria | Loss |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: May 8 - May 15 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Federico Delbonis | Win | |
| Second Round | Karen Khachanov | Loss |
| Mutua Madrid Open | ||
| Surface: Hard | Date: Apr. 28 - May 8 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Botic van de Zandschulp | Loss |
| Barcelona Open Banc Sabadell | ||
| Surface: Clay | Date: Apr. 18 - Apr. 24 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Bernabe Zapata Miralles | Win | |
| Third Round | Lorenzo Sonego | Win | |
| Quarterfinals | Casper Ruud | Win | |
| Semifinals | Diego Schwartzman | Win | |
| Final | Carlos Alcaraz | Loss |
| Rolex Monte-Carlo Masters | ||
| Surface: Clay | Date: Apr. 10 - Apr. 17 | Seed: 13 |
| Round | Opponent | W / L | Result |
| First Round | Sebastian Baez | Win | |
| Second Round | Alexander Bublik | Win | |
| Third Round | Alexander Zverev | Loss |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 22 - Apr. 3 | Seed: 17 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | David Goffin | Win | |
| Third Round | Jannik Sinner | Loss |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 9 - Mar. 20 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jaume Munar | Loss |
| Abierto Mexicano Telcel presentado por HSBC | ||
| Surface: Hard | Date: Feb. 21 - Feb. 26 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Oscar Otte | Win | |
| Second Round | Marcos Giron | Loss |
| Rio Open presented by Claro HDTV | ||
| Surface: Clay | Date: Feb. 14 - Feb. 20 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Fabio Fognini | Loss |
| Australian Open | ||
| Surface: Hard | Date: Jan. 17 - Jan. 30 | Seed: 19 |
| Round | Opponent | W / L | Result |
| First Round | Tomas Martin Etcheverry | Win | |
| Second Round | Tallon Griekspoor | Win | |
| Third Round | Sebastian Korda | Win | |
| Fourth Round | Matteo Berrettini | Loss |
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