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| Roland Garros | ||
| Surface: Red Clay | Date: Sep. 27 - Oct. 11 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Jannik Sinner | Loss | 5-7, 0-6, 3-6 |
| Internazionali BNL d'Italia | ||
| Surface: Red Clay | Date: Sep. 14 - Sep. 21 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Marin Cilic | Loss | 2-6, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 31 - Sep. 13 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Reilly Opelka | Win | 7-6 (7-2), 3-6, 6-1, 6-4 |
| Second Round | Lloyd Harris | Win | 7-6 (8-6), 4-6, 6-1, 6-4 |
| Third Round | Filip Krajinovic | Win | 6-1, 7-6 (7-5), 6-4 |
| Fourth Round | Denis Shapovalov | Loss | 7-6 (7-0), 3-6, 4-6, 3-6 |
| Western & Southern Open | ||
| Surface: Hard | Date: Aug. 22 - Aug. 29 | Seed: 7 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Borna Coric | Win | 7-6 (8-6), 6-4 |
| Third Round | Jan-Lennard Struff | Loss | 4-6, 6-3, 4-6 |
| Open 13 Provence | ||
| Surface: Hard | Date: Feb. 17 - Feb. 23 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Egor Gerasimov | Loss | 4-6, 6-7 (5-7) |
| ABN AMRO World Tennis Tournament | ||
| Surface: Hard | Date: Feb. 10 - Feb. 16 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Robin Haase | Win | 3-6, 7-6 (7-5), 6-4 |
| Second Round | Jannik Sinner | Loss | 6-7 (7-9), 5-7 |
| Open Sud de France | ||
| Surface: Hard | Date: Feb. 3 - Feb. 9 | Seed: 2 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Alexander Bublik | Win | 6-3, 7-6 (11-9) |
| Quarterfinals | Pierre-Hugues Herbert | Win | 6-4, 7-6 (7-5) |
| Semifinals | Vasek Pospisil | Loss | 3-6, 6-1, 5-7 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 20 - Feb. 2 | Seed: 11 |
| Round | Opponent | W / L | Result |
| First Round | Jeremy Chardy | Win | 6-4, 6-3, 6-1 |
| Second Round | Pierre-Hugues Herbert | Win | 6-1, 6-4, 4-6, 1-6, 6-3 |
| Third Round | Andrey Rublev | Loss | 6-2, 6-7 (3-7), 4-6, 6-7 (4-7) |
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