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| Moselle Open | ||
| Surface: Hard | Date: Sep. 16 - Sep. 22 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Peter Gojowczyk | Win | 7-5, 6-4 |
| Second Round | Fernando Verdasco | Win | 3-6, 6-4, 6-3 |
| Quarterfinals | Lucas Pouille | Loss | 6-4, 5-7, 2-6 |
| US Open | ||
| Surface: Hard | Date: Aug. 26 - Sep. 8 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Cedrik-Marcel Stebe | Loss | 3-6, 6-4, 4-6, 6-7 (6-8) |
| Winston-Salem Open | ||
| Surface: Hard | Date: Aug. 18 - Aug. 24 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Tomas Berdych | Win | 3-6, 7-5, 6-1 |
| Third Round | Frances Tiafoe | Loss | 2-6, 0-0 Retired |
| Hamburg Open | ||
| Surface: Red Clay | Date: Jul. 22 - Jul. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Laslo Djere | Win | 6-3, 6-3 |
| Second Round | Martin Klizan | Win | 6-7 (6-8), 7-5, 6-1 |
| Quarterfinals | Alexander Zverev | Loss | 6-2, 5-7, 2-6 |
| Plava Laguna Croatia Open Umag | ||
| Surface: Clay | Date: Jul. 15 - Jul. 21 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Taro Daniel | Win | 7-5, 7-6 (7-4) |
| Second Round | Attila Balazs | Loss | 3-6, 7-6 (7-1), 6-7 (5-7) |
| Wimbledon | ||
| Surface: Grass | Date: Jul. 1 - Jul. 14 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Dominik Koepfer | Loss | 3-6, 6-4, 6-7 (9-11), 1-6 |
| Roland Garros | ||
| Surface: Red Clay | Date: May 26 - Jun. 9 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Frances Tiafoe | Win | 6-2, 4-6, 6-3, 3-6, 6-0 |
| Second Round | Roberto Carballes Baena | Win | 6-4, 6-4, 6-7 (1-7), 3-6, 8-6 |
| Third Round | Stefanos Tsitsipas | Loss | 5-7, 3-6, 7-6 (7-5), 6-7 (6-8) |
| Gazprom Hungarian Open | ||
| Surface: Red Clay | Date: Apr. 22 - Apr. 28 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Andreas Seppi | Win | 6-2, 6-7 (3-7), 7-5 |
| Second Round | Radu Albot | Win | 7-5, 6-4 |
| Quarterfinals | Borna Coric | Win | 6-4, 7-5 |
| Semifinals | Pierre-Hugues Herbert | Win | 6-2, 6-2 |
| Final | Matteo Berrettini | Loss | 6-4, 3-6, 1-6 |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 19 - Mar. 31 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Pierre-Hugues Herbert | Win | 6-4, 6-4 |
| Second Round | Stan Wawrinka | Win | 5-7, 6-2, 7-6 (7-5) |
| Third Round | Roger Federer | Loss | 5-7, 3-6 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 6 - Mar. 17 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Mikhail Kukushkin | Win | 6-3, 6-4 |
| Second Round | David Goffin | Win | 6-3, 6-3 |
| Third Round | Daniil Medvedev | Win | 6-3, 6-2 |
| Fourth Round | Rafael Nadal | Loss | 3-6, 4-6 |
| Open 13 Provence | ||
| Surface: Hard | Date: Feb. 18 - Feb. 24 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Hubert Hurkacz | Loss | 3-6, 2-6 |
| Open Sud de France | ||
| Surface: Hard | Date: Feb. 4 - Feb. 10 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Nicolas Mahut | Win | 7-6 (9-7), 6-4 |
| Second Round | David Goffin | Win | 6-4, 6-4 |
| Quarterfinals | Tomas Berdych | Loss | 6-7 (3-7), 7-6 (7-5), 5-7 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 14 - Jan. 27 | Seed: None |
| Round | Opponent | W / L | Result |
| First Round | Marco Cecchinato | Win | 4-6, 0-6, 6-1, 7-6(10-8), 6-4 |
| Second Round | Evgeny Donskoy | Win | 6-4, 7-6 (10-8), 7-6 (7-2) |
| Third Round | Borna Coric | Loss | 6-2, 3-6, 4-6, 3-6 |
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