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| Fayez Sarofim & Co. US Men's Clay Court Championship | ||
| Surface: Clay | Date: Apr. 9 - Apr. 15 | Seed: 1 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Henri Laaksonen | Win | 6-4, 6-2 |
| Quarterfinals | Steve Johnson | Loss | 6-7 (4-7), 6-4, 6-7 (5-7) |
| Miami Open presented by Itau | ||
| Surface: Hard | Date: Mar. 20 - Apr. 1 | Seed: 14 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Jiri Vesely | Win | 7-6 (7-3), 1-6, 6-3 |
| Third Round | Mikhail Youzhny | Win | 6-4, 6-3 |
| Fourth Round | Marin Cilic | Win | 7-6 (7-0), 6-3 |
| Quarterfinals | Hyeon Chung | Win | 6-1, 6-4 |
| Semifinals | Juan Martin Del Potro | Win | 6-1, 7-6 (7-2) |
| Final | Alexander Zverev | Win | 6-7 (4-7), 6-4, 6-4 |
| BNP Paribas Open | ||
| Surface: Hard | Date: Mar. 7 - Mar. 18 | Seed: 15 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Gael Monfils | Loss | 7-6 (7-5), 6-7 (3-7), 5-7 |
| Abierto Mexicano TELCEL | ||
| Surface: Hard | Date: Feb. 26 - Mar. 3 | Seed: 8 |
| Round | Opponent | W / L | Result |
| First Round | Ryan Harrison | Loss | 3-6, 6-7 (5-7) |
| Delray Beach Open | ||
| Surface: Hard | Date: Feb. 19 - Feb. 25 | Seed: 6 |
| Round | Opponent | W / L | Result |
| First Round | Radu Albot | Win | 5-7, 6-3, 6-4 |
| Second Round | Peter Gojowczyk | Loss | 6-7 (3-7), 7-6 (7-4), 6-7 (5-7) |
| New York Open | ||
| Surface: Hard | Date: Feb. 12 - Feb. 18 | Seed: 3 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Radu Albot | Loss | 6-7 (5-7), 6-3, 3-6 |
| Australian Open | ||
| Surface: Hard | Date: Jan. 15 - Jan. 28 | Seed: 16 |
| Round | Opponent | W / L | Result |
| First Round | Matthew Ebden | Loss | 4-6, 6-3, 3-6, 3-6 |
| ASB Classic | ||
| Surface: Hard | Date: Jan. 1 - Jan. 13 | Seed: 4 |
| Round | Opponent | W / L | Result |
| First Round | Bye | ||
| Second Round | Hyeon Chung | Loss | 6-7 (3-7), 7-5, 2-6 |
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